- 专利标题: Pyrrole inhibitors of S-nitrosoglutathione reductase as therapeutic agents
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申请号: US13057173申请日: 2009-08-14
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公开(公告)号: US08470857B2公开(公告)日: 2013-06-25
- 发明人: Jan Wasley , Gary J. Rosenthal , Xicheng Sun , Sarah Strong , Jian Qiu
- 申请人: Jan Wasley , Gary J. Rosenthal , Xicheng Sun , Sarah Strong , Jian Qiu
- 申请人地址: US CO Boulder
- 专利权人: N30 Pharmaceuticals, Inc.
- 当前专利权人: N30 Pharmaceuticals, Inc.
- 当前专利权人地址: US CO Boulder
- 代理机构: Swanson & Bratschun, L.L.C.
- 国际申请: PCT/US2009/053925 WO 20090814
- 国际公布: WO2010/019905 WO 20100218
- 主分类号: A61K31/40
- IPC分类号: A61K31/40 ; A61K31/4439 ; C07D401/04 ; C07D403/10
摘要:
The present invention is directed to inhibitors of S-nitrosoglutathione reductase (GSNOR), pharmaceutical compositions comprising such GSNOR inhibitors, and methods of making and using the same.
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