Invention Grant
US08481531B2 Bicyclic heterocyclyl derivatives as FGFR kinase inhibitors for therapeutic use
有权
双环杂环基衍生物作为治疗用途的FGFR激酶抑制剂
- Patent Title: Bicyclic heterocyclyl derivatives as FGFR kinase inhibitors for therapeutic use
- Patent Title (中): 双环杂环基衍生物作为治疗用途的FGFR激酶抑制剂
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Application No.: US13264593Application Date: 2010-04-15
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Publication No.: US08481531B2Publication Date: 2013-07-09
- Inventor: Gordon Saxty , Valerio Berdini , Eddy Jean Edgard Freyne , Alexandra Papanikos , Pascal Benderitter , Werner Constant Johan Embrechts , Berthold Wroblowski , Rhalid Akkari
- Applicant: Gordon Saxty , Valerio Berdini , Eddy Jean Edgard Freyne , Alexandra Papanikos , Pascal Benderitter , Werner Constant Johan Embrechts , Berthold Wroblowski , Rhalid Akkari
- Applicant Address: GB Cambridge
- Assignee: Astex Therapeutics Ltd
- Current Assignee: Astex Therapeutics Ltd
- Current Assignee Address: GB Cambridge
- Agency: Heslin Rothenberg Farley & Mesiti P.C.
- Priority: GB0906472.6 20090415
- International Application: PCT/GB2010/050617 WO 20100415
- International Announcement: WO2010/119284 WO 20101021
- Main IPC: A61K31/5377
- IPC: A61K31/5377 ; A61K31/437 ; A61K31/496 ; C07D413/02 ; C07D471/04 ; C07D401/02 ; C07D239/20
Abstract:
The invention relates to new bicyclic heterocyclyl derivatives of formula (I), to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.
Public/Granted literature
- US20120035171A1 BICYCLIC HETEROCYCLYL DERIVATIVES AS FGFR KINASE INHIBITORS FOR THERAPEUTIC USE Public/Granted day:2012-02-09
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