A method and apparatus of transmitting an uplink control signal in a wireless communication system is provided. A user equipment receives pieces of resource allocation information about a plurality of respective uplink control channels, and transmits the uplink control signal through one of the plurality of uplink control channels. Radio resources sequentially adjacent to each other on a basis of one reference uplink control channel, selected from the plurality of uplink control channels, are allocated to the respective uplink control channels. And the resource allocation information comprises size of the radio resources allocated to each of the plurality of uplink control channels within a resource region in which the plurality of uplink control channels is configured.