发明授权
- 专利标题: Piperazinodihydrothienopyrimidine derivatives
- 专利标题(中): 哌嗪二氢噻吩并嘧啶衍生物
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申请号: US12738425申请日: 2008-10-16
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公开(公告)号: US08486948B2公开(公告)日: 2013-07-16
- 发明人: Pascale Pouzet , Christoph Hoenke , Peter Nickolaus , Rolf Goeggel , Thomas Fox , Dennis Fiegen , Klaus Klinder
- 申请人: Pascale Pouzet , Christoph Hoenke , Peter Nickolaus , Rolf Goeggel , Thomas Fox , Dennis Fiegen , Klaus Klinder
- 申请人地址: DE Ingelheim am Rhein
- 专利权人: Boehringer Ingelheim International GmbH
- 当前专利权人: Boehringer Ingelheim International GmbH
- 当前专利权人地址: DE Ingelheim am Rhein
- 代理商 Michael P. Morris; Wendy A. Petka; Timothy X. Witkowski
- 优先权: EP07118906 20071019
- 国际申请: PCT/EP2008/063970 WO 20081016
- 国际公布: WO2009/050236 WO 20090423
- 主分类号: C07D495/04
- IPC分类号: C07D495/04 ; A61K31/519 ; A61P25/28 ; A61P25/24 ; A61P25/22 ; A61P29/00 ; A61P11/06
摘要:
The invention relates to the novel dihydrothienopyrimidine sulfoxides of formula (I) and to the pharmacologically acceptable salts thereof, wherein X represents SO or SO2, preferably however SO, and wherein R3, R4, R4′, R5, R6 and R7 are defined as in claim 1. The invention also relates to pharmaceutical compositions containing said compounds. The novel dihydrothienopyrimidine sulfoxides are suitable for use in the treatment of respiratory or gastrointestinal disorders or diseases, inflammatory diseases of the joints, the skin or the eyes, diseases of the peripheral or central nervous system or cancers.
公开/授权文献
- US20110046096A1 NOVEL PIPERAZINO-DIHYDROTHIENOPYRIMIDINE DERIVATIVES 公开/授权日:2011-02-24