A system and method for proactively monitoring the status of packages shipped by a package delivery carrier including intervening when certain conditions arise. The system identifies certain packages are requiring proactive monitoring and intervention, and monitors a variety of conditions, including system-wide impacts and package-level specific impacts, which may necessitate intervention by carrier personnel. Intervention may include various exception handling actions, including upgrading the level of service, stabilizing the temperature of the package, inspecting damage to the package. The carrier may notify the consignee or consignor of such detected conditions and may then communicate with appropriate individuals involved with the package delivery to ascertain the most appropriate action necessary. The system facilitates communicating such information to appropriate carrier personnel. The system may also maintain a real-time case log regarding the package, which can be accessed by service representative, package handling personnel, and said appropriate individuals.