Invention Grant
US08492127B2 Bacillus coagulans strains and their applications in L-lactic acid production
有权
凝结芽孢杆菌菌株及其在L-乳酸生产中的应用
- Patent Title: Bacillus coagulans strains and their applications in L-lactic acid production
- Patent Title (中): 凝结芽孢杆菌菌株及其在L-乳酸生产中的应用
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Application No.: US13698708Application Date: 2010-11-22
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Publication No.: US08492127B2Publication Date: 2013-07-23
- Inventor: Ping Xu , Limin Wang , Bo Zhao , Cuiqing Ma , Fei Su , Fei Tao , Hongzhi Tang
- Applicant: Ping Xu , Limin Wang , Bo Zhao , Cuiqing Ma , Fei Su , Fei Tao , Hongzhi Tang
- Applicant Address: CN Shanghai
- Assignee: Shanghai Jiao Tong University
- Current Assignee: Shanghai Jiao Tong University
- Current Assignee Address: CN Shanghai
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner, LLP
- Priority: CN201010176868 20100520
- International Application: PCT/CN2010/001871 WO 20101122
- International Announcement: WO2011/143800 WO 20111124
- Main IPC: C12P7/56
- IPC: C12P7/56

Abstract:
The invention is concerned with the strains of B. coagulans for lactic acid production and the related methods, in which the carbon sources are pentose or hexose or the agricultural or industrial wastes containing pentose or hexose or a mixture of both. According to the invention, the highest amount of L-lactic acid produced from glucose is 173 g/L, the optical purity is over 99%, the yield is up to 0.98, and the productivity is up to 2.4 g/L per hour. The highest amount of L-lactic acid produced from xylose is 195 g/L, the optical purity is over 99%, the yield is up to 0.98, and the productivity is up to 2.7 g/L per hour. The highest amount of L-lactic acid produced from reducing sugars in xylitol byproducts is 106 g/L, the optical purity is over 99%, and the productivity is up to 2.08 g/L per hour. The B. coagulans strains XZL4 (DSM No. 23183) and XZL9 (DSM No. 23184) of the invention can directly utilize various reducing sugars in xylitol byproducts to produce high amounts of L-lactic acid, which improves the production efficiency at low costs, and the strains are, thus, appropriate for industrial productions.
Public/Granted literature
- US20130143286A1 BACILLUS COAGULANS STRAINS AND THEIR APPLICATIONS IN L-LACTIC ACID PRODUCTION Public/Granted day:2013-06-06
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