发明授权
- 专利标题: Antibacterial agents
- 专利标题(中): 抗菌剂
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申请号: US12678767申请日: 2008-09-22
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公开(公告)号: US08492414B2公开(公告)日: 2013-07-23
- 发明人: David John Haydon , Ian Collins , Lloyd George Czaplewski
- 申请人: David John Haydon , Ian Collins , Lloyd George Czaplewski
- 申请人地址: AU Notting Hill, Victoria
- 专利权人: Biota Scientific Management Pty Ltd
- 当前专利权人: Biota Scientific Management Pty Ltd
- 当前专利权人地址: AU Notting Hill, Victoria
- 代理机构: Banner & Witcoff, Ltd.
- 优先权: GB0718335.3 20070920
- 国际申请: PCT/GB2008/003200 WO 20080922
- 国际公布: WO2009/037485 WO 20090326
- 主分类号: A61K31/41
- IPC分类号: A61K31/41
摘要:
Compounds of formula (IA) or (IB) have antibacterial activity: wherein W is ═CH— or ═N—; Ri and R2 are independently selected from hydrogen, fluoro and chloro, provided that Ri and R2 are not each hydrogen when W is ═CH—; n is 0 or 1; X is —O—, —S—, or —CH2—; and Q is (i) a phenyl radical, a naphthyl radical, a monocyclic carbocyclic or heteroaryl radical having 3 to 6 ring atoms, or a bicyclic heteroaryl radical having 5 to 10 ring atoms, any of which radicals being optionally substituted; or (ii) an optionally substituted C1-C6 alkyl, C2-C6 alkenyl, or C2-C6 alkynyl radical, which may optionally be interrupted by —O—, —S—, —S(O)—, —S(O2)—, —NH—, —N(CH3)—, —N(CH2CH3)—, —C—K═Oh or —C(═O)—O—.
公开/授权文献
- US20100273837A1 ANTIBACTERIAL AGENTS 公开/授权日:2010-10-28
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