Embodiments of the present invention provide an approach for providing non-disruptive transitioning of application replication configurations and proactive analysis of possible error scenarios. Specifically, under embodiments of the present invention, a common integration model (CIM)-compatible representation of a system replication plan is provided in a computer data structure. Based on the representation, a hierarchical tree data structure having a set of nodes is created. A set of system configuration updates pertaining to the set of nodes are then classified (e.g., based upon the type of configuration update). Once the set of nodes has been classified, the set of nodes may then be analyzed to determine if any nodes of the set are isomorphic. If so, the plan can be modified accordingly. In any event, the replication plan (or modified replication plan) may then be implemented.