发明授权
- 专利标题: Aqueous liquid preparation containing 2-amino-3-(4-bromobenzoyl)phenylacetic acid
-
申请号: US13353653申请日: 2012-01-19
-
公开(公告)号: US08497304B2公开(公告)日: 2013-07-30
- 发明人: Shirou Sawa , Shuhei Fujita
- 申请人: Shirou Sawa , Shuhei Fujita
- 申请人地址: JP Osaka
- 专利权人: Senju Pharmaceutical Co., Ltd.
- 当前专利权人: Senju Pharmaceutical Co., Ltd.
- 当前专利权人地址: JP Osaka
- 代理机构: Wenderoth, Lind & Ponack, LLP.
- 优先权: JP2003-012427 20030121
- 主分类号: A01N37/18
- IPC分类号: A01N37/18 ; A01N37/44 ; A01N37/10 ; A61K31/165 ; A61K31/24 ; A61K31/19
摘要:
An aqueous liquid preparation of the present invention containing 2-amino-3-(4-bromobenzoyl)phenylacetic acid or its pharmacologically acceptable salt or a hydrate thereof, an alkyl aryl polyether alcohol type polymer such as tyloxapol, or a polyethylene glycol fatty acid ester such as polyethylene glycol monostearate is stable. Since even in the case where a preservative is incorporated into said aqueous liquid preparation, the preservative exhibits a sufficient preservative effect for a long time, said aqueous liquid preparation in the form of an eye drop is useful for the treatment of blepharitis, conjunctivitis, scleritis, and postoperative inflammation. Also, the aqueous liquid preparation of the present invention in the form of a nasal drop is useful for the treatment of allergic rhinitis and inflammatory rhinitis (e.g. chronic rhinitis, hypertrophic rhinitis, nasal polyp, etc.).