发明授权
- 专利标题: Phosphonic acid compounds as inhibitors of serine proteases
- 专利标题(中): 膦酸化合物作为丝氨酸蛋白酶的抑制剂
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申请号: US13471876申请日: 2012-05-15
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公开(公告)号: US08497373B2公开(公告)日: 2013-07-30
- 发明人: Michael N. Greco , Harold R. Almond, Jr. , Lawrence de Garavilla , Michael J. Hawkins , Michael J. Humora , Yun Qian , Donald Gilmore Walker , Sergio Cesco-Cancian , Christopher Norman Nilsen , Mitul N. Patel , Kirk Leonard Sorgi , Eugene Powell
- 申请人: Michael N. Greco , Harold R. Almond, Jr. , Lawrence de Garavilla , Michael J. Hawkins , Michael J. Humora , Yun Qian , Donald Gilmore Walker , Sergio Cesco-Cancian , Christopher Norman Nilsen , Mitul N. Patel , Kirk Leonard Sorgi , Eugene Powell
- 申请人地址: US NJ Raritan
- 专利权人: Ortho-McNeil Pharmaceutical, Inc.
- 当前专利权人: Ortho-McNeil Pharmaceutical, Inc.
- 当前专利权人地址: US NJ Raritan
- 代理商 Yuriy P. Stercho
- 主分类号: C07D241/02
- IPC分类号: C07D241/02 ; C07F9/02 ; A61K31/4965
摘要:
The present invention is directed to phosphonic acid compounds useful as serine protease inhibitors, compositions thereof and methods for treating inflammatory and serine protease mediated disorders.
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