发明授权
- 专利标题: HIV protease inhibitors
- 专利标题(中): HIV蛋白酶抑制剂
-
申请号: US13322184申请日: 2010-05-18
-
公开(公告)号: US08497383B2公开(公告)日: 2013-07-30
- 发明人: Craig A. Coburn , M. Katharine Holloway , Joseph P. Vacca
- 申请人: Craig A. Coburn , M. Katharine Holloway , Joseph P. Vacca
- 申请人地址: US NJ Rahway
- 专利权人: Merck Sharp & Dohme Corp.
- 当前专利权人: Merck Sharp & Dohme Corp.
- 当前专利权人地址: US NJ Rahway
- 代理商 Sheldon O. Heber; Raynard Yuro
- 国际申请: PCT/US2010/035200 WO 20100518
- 国际公布: WO2010/138338 WO 20101202
- 主分类号: C07D207/14
- IPC分类号: C07D207/14 ; A61K31/40
摘要:
Compounds of Formula (I) are disclosed; wherein XA, k, A, B, R3A, R3B, R4 and R5 are defined herein. The compounds of Formula (I) are HIV protease inhibitors. The compounds and their pharmaceutically acceptable salts are useful for the prophylaxis or treatment of infection by HIV and the prophylaxis, treatment, or delay in the onset of AIDS. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.
公开/授权文献
- US20120142752A1 HIV PROTEASE INHIBITORS 公开/授权日:2012-06-07
信息查询