- 专利标题： Measuring circulating therapeutic antibody, antigen and antigen/antibody complexes using ELISA assays
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申请号： US13543560申请日： 2012-07-06
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公开(公告)号： US08501423B2公开(公告)日： 2013-08-06
- 发明人: Maher Albitar , Michael J. Keating , Taghi Manshouri
- 申请人： Maher Albitar , Michael J. Keating , Taghi Manshouri
- 申请人地址： US TX Austin
- 专利权人： Board of Regents, The University of Texas System
- 当前专利权人： Board of Regents, The University of Texas System
- 当前专利权人地址： US TX Austin
- 代理机构： Parker Highlander PLLC
- 主分类号： G01N31/00
- IPC分类号： G01N31/00 ; G01N33/53
摘要：
The present invention relates to the field of immunology and hyperproliferative diseases. More specifically, the present invention relates to a method of detecting and monitoring therapeutic antibody:antigen complex, soluble antigen and soluble therapeutic antibody, wherein a patient has undergone at least one course of immunotherapy. Yet further, levels of therapeutic antibody:antigen complexes, soluble antigens or soluble therapeutic antibodies may be measured and used to stage or monitor a hyperproliferative disease.
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