Invention Grant
US08501488B2 Compound for derivatizing polypeptides and method for sequencing and quantifying amino acids in polypeptides using the same 有权
用于衍生多肽的化合物和使用其进行多肽中的氨基酸测序和定量的方法

Compound for derivatizing polypeptides and method for sequencing and quantifying amino acids in polypeptides using the same
Abstract:
The present invention relates to a compound for N-terminal substitution of polypeptides which is used in sequencing and quantifying amino acids and a method for sequencing and quantifying an amino acid sequence using the same. The method for sequencing and quantifying amino acids in accordance with the present invention leads to a relative quantitative analysis of proteins with very high reliability, and can distinctively discriminate between y-type ions and b-type ions on the MS/MS spectra, providing the means for realization of high-reliability protein identification.
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