- 专利标题： Variant activin receptor polypeptides and uses thereof
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申请号： US13329897申请日： 2011-12-19
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公开(公告)号： US08501678B2公开(公告)日： 2013-08-06
- 发明人: Jeonghoon Sun , Lei-Ting Tony Tam , Hui-Quan Han , Keith Soo-Nyung Kwak , Xiaolan Zhou , John Lu
- 申请人： Jeonghoon Sun , Lei-Ting Tony Tam , Hui-Quan Han , Keith Soo-Nyung Kwak , Xiaolan Zhou , John Lu
- 申请人地址： US CA Brisbane
- 专利权人： Atara Biotherapeutics, Inc.
- 当前专利权人： Atara Biotherapeutics, Inc.
- 当前专利权人地址： US CA Brisbane
- 代理机构： Fenwick & West LLP
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; A61P35/00
摘要：
The present invention provides variant activin IIB soluble receptor polypeptides and proteins capable of binding and inhibiting the activities of activin A, myostatin, or GDF-11. The present invention also provides polynucleotides, vectors and host cells capable of producing the variant polypeptides and proteins. Compositions and methods for treating muscle-wasting and other diseases and disorders are also provided.
公开/授权文献
- US20120328595A1 VARIANT ACTIVIN RECEPTOR POLYPEPTIDES AND USES THEREOF 公开/授权日：2012-12-27
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