发明授权
- 专利标题： Substituted heteroarylamide oxazepinopyrimidone derivatives
- 专利标题（中）： 取代的杂芳基酰胺氧氮杂并嘧啶衍生物
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申请号： US12844270申请日： 2010-07-27
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公开(公告)号： US08501728B2公开(公告)日： 2013-08-06
- 发明人: Aude Fayol , Alistair Lochead , Mourad Saady , Julien Vache , Philippe Yaiche
- 申请人： Aude Fayol , Alistair Lochead , Mourad Saady , Julien Vache , Philippe Yaiche
- 申请人地址： FR Paris JP Osaka
- 专利权人： Sanofi,Mitsubishi Tanabe Pharma Corporation
- 当前专利权人： Sanofi,Mitsubishi Tanabe Pharma Corporation
- 当前专利权人地址： FR Paris JP Osaka
- 代理商 Kelly L. Bender
- 优先权： EP08290077 20080129
- 主分类号： A61P3/00
- IPC分类号： A61P3/00 ; A61P25/00 ; A61P35/00 ; A61K31/553 ; C07D498/04
摘要：
The disclosure relates to a series pyrimidone derivatives represented by formula (I) or a salt thereof, or a solvate thereof or a hydrate thereof: wherein: Y, Z, R1, R2, R3, R4 and n are as defined in the disclosure. Also disclosed are methods of preparing the compounds of formula (I), intermediates therefor and their utility in treating a variety of disease conditions.