发明授权
- 专利标题: Platinum complex and pharmaceutical composition containing the same
- 专利标题(中): 铂复合物和含有相同的药物组合物
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申请号: US13060906申请日: 2009-08-25
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公开(公告)号: US08501977B2公开(公告)日: 2013-08-06
- 发明人: Hisae Arai , Masaji Ohno , Hisao Kondo , Ikuko Arai
- 申请人: Hisae Arai , Masaji Ohno , Hisao Kondo , Ikuko Arai
- 申请人地址: JP Kashiwa-Shi, Chiba
- 专利权人: Unitech Co., Ltd.
- 当前专利权人: Unitech Co., Ltd.
- 当前专利权人地址: JP Kashiwa-Shi, Chiba
- 代理机构: Bacon & Thomas, PLLC
- 优先权: JP2008-225698 20080903; JP2009-155399 20090630
- 国际申请: PCT/JP2009/004077 WO 20090825
- 国际公布: WO2010/026711 WO 20100311
- 主分类号: C07F15/00
- IPC分类号: C07F15/00 ; A61K31/28
摘要:
A new platinum complex which has strong antitumor activity and has effect with smaller doses and a pharmaceutical composition containing the same are provided. A spiro[4,4]nonane-1,6-diamineplatinum(II) complex which is represented by a following general formula (A). (In the formula, X and Y are same or different, and X and Y represent halogen atoms respectively, or X and Y cooperatively represent a divalent residue which is described by a formula (Z).) The platinum complex has a strong antitumor activity and is efficacious as a therapeutic agent for malignant tumors.
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