发明授权
US08507224B2 Vectors and yeast strains for protein production: Ca2+ ATPase overexpression
失效
用于蛋白质生产的载体和酵母菌株：Ca2 + ATPase过表达
- 专利标题： Vectors and yeast strains for protein production: Ca2+ ATPase overexpression
- 专利标题（中）： 用于蛋白质生产的载体和酵母菌株：Ca2 + ATPase过表达
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申请号： US13057807申请日： 2009-08-10
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公开(公告)号： US08507224B2公开(公告)日： 2013-08-13
- 发明人: Byung-Kwon Choi
- 申请人： Byung-Kwon Choi
- 申请人地址： US NH Lebanon
- 专利权人： GlycoFi, Inc.
- 当前专利权人： GlycoFi, Inc.
- 当前专利权人地址： US NH Lebanon
- 代理商 John David Reilly; Immac J. Thampoe
- 国际申请： PCT/US2009/053247 WO 20090810
- 国际公布： WO2010/019487 WO 20100218
- 主分类号： C12P21/00
- IPC分类号： C12P21/00 ; C12N1/15 ; C12N1/19
摘要：
Lower eukaryote host cells in which an endogenous or heterologous Ca2+ ATPase is overexpressed are described. Also described are lower eukaryote host cells in which a calreticulin and/or ERp57 protein are overexpressed. These host cells are useful for producing recombinant glycoproteins that have reduced O-glycosylation.
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