发明授权
- 专利标题: Substituted indole/indazole-pyrimidinyl compounds
- 专利标题(中): 取代的吲哚/吲唑 - 嘧啶基化合物
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申请号: US13312720申请日: 2011-12-06
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公开(公告)号: US08507499B2公开(公告)日: 2013-08-13
- 发明人: Shaun R. Selness , Joseph B. Monahan , John F. Schindler , Balekudru Devadas
- 申请人: Shaun R. Selness , Joseph B. Monahan , John F. Schindler , Balekudru Devadas
- 申请人地址: US MO St. Louis
- 专利权人: Confluence Life Sciences, Inc.
- 当前专利权人: Confluence Life Sciences, Inc.
- 当前专利权人地址: US MO St. Louis
- 代理机构: Harness, Dickey & Pierce, P.L.C.
- 代理商 J. Timothy Keane; Kisuk Lee
- 主分类号: A61K31/506
- IPC分类号: A61K31/506 ; C07D403/14
摘要:
The present disclosure provides indole/indazole-pyrimidinyl compounds useful in the treatment of p38 kinase mediated diseases, such as lymphoma and auto-inflammatory disease, having the structure of Formula (I): wherein W, X, R1, R2, R3, R4, R5 and R6 are as defined in the detailed description; pharmaceutical compositions comprising at least one of the compounds; and methods for treating p38 kinase mediated diseases using the compound.
公开/授权文献
- US20120142696A1 SUBSTITUTED INDOLE/INDAZOLE-PYRIMIDINYL COMPOUNDS 公开/授权日:2012-06-07
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