发明授权
- 专利标题： Inhibitors of the BMP signaling pathway
- 专利标题（中）： BMP信号通路抑制剂
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申请号： US12922122申请日： 2009-03-13
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公开(公告)号： US08507501B2公开(公告)日： 2013-08-13
- 发明人: Paul B. Yu , Gregory D. Cuny , Kenneth D. Bloch , Randall T. Peterson , Charles C. Hong
- 申请人： Paul B. Yu , Gregory D. Cuny , Kenneth D. Bloch , Randall T. Peterson , Charles C. Hong
- 申请人地址： US MA Boston US MA Boston
- 专利权人： The Brigham and Women's Hospital, Inc.,The General Hospital Corporation
- 当前专利权人： The Brigham and Women's Hospital, Inc.,The General Hospital Corporation
- 当前专利权人地址： US MA Boston US MA Boston
- 代理机构： Ropes & Gray LLP
- 国际申请： PCT/US2009/001606 WO 20090313
- 国际公布： WO2009/114180 WO 20090917
- 主分类号： A01N43/90
- IPC分类号： A01N43/90 ; A61K31/519 ; C07D487/00
摘要：
The present invention provides small molecule inhibitors of BMP signaling. These compounds may be used to modulate cell growth, differentiation, proliferation, and apoptosis, and thus may be useful for treating diseases or conditions associated with BMP signaling, including inflammation, cardiovascular disease, hematological disease, cancer, and bone disorders, as well as for modulating cellular differentiation and/or proliferation.
公开/授权文献
- US20110053930A1 INHIBITORS OF THE BMP SIGNALING PATHWAY 公开/授权日：2011-03-03
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