The present invention provides a control circuit for LED driver. A voltage-feedback circuit is coupled to LEDs to sense a voltage-feedback signal for generating a voltage loop signal. Current sources are coupled to the LEDs to control LED currents. A detection circuit is connected to sense voltages of current sources for generating a current-source loop signal in response to a minimum voltage of the current sources. Furthermore, a buffer circuit generates a feedback signal in accordance with the voltage loop signal and the current-source loop signal. The feedback signal is coupled to limit a maximum voltage of the LEDs and regulate the minimum voltage across the current sources.