A device for applying successive resilient ligating bands to tissue is described. A sleeve has an opening at a front end thereof, and axially extending arms having axially extending spaces therebetween. Band-support surfaces located on the arms extend from the front end for accommodating a plurality of ligating bands. A first tube around which the sleeve is located, is reciprocal relative to the sleeve and has axially extending fingers provided with forward-facing pushing surfaces. Means are provided for drawing tissue to be ligated into the opening. In use, the pushing surfaces push the bands forwardly so that they ride along the band-support surfaces of the sleeve to each lie nearer the front end, a foremost band being pushed off the front end of the sleeve onto the tissue.