发明授权
- 专利标题: Pyrazolo[1,5-a]pyridines as MARK inhibitors
- 专利标题(中): 吡唑并[1,5-a]吡啶作为MARK抑制剂
-
申请号: US13057510申请日: 2009-07-27
-
公开(公告)号: US08518911B2公开(公告)日: 2013-08-27
- 发明人: Jason D. Katz , Sandra L. Knowles , James P. Jewell , David L. Sloman , Matthew G. Stanton , Njamkou Noucti
- 申请人: Jason D. Katz , Sandra L. Knowles , James P. Jewell , David L. Sloman , Matthew G. Stanton , Njamkou Noucti
- 申请人地址: US NJ Rahway
- 专利权人: Merck Sharp & Dohme Corp.
- 当前专利权人: Merck Sharp & Dohme Corp.
- 当前专利权人地址: US NJ Rahway
- 代理商 Susan L. Hess; Raynard Yuro; Gerard M. Devlin
- 国际申请: PCT/US2009/051785 WO 20090727
- 国际公布: WO2010/017046 WO 20100211
- 主分类号: A61K31/675
- IPC分类号: A61K31/675 ; A61K31/437 ; A61K31/496 ; A61K31/397
摘要:
The invention encompasses pyrazolo[1,5-a]pyridine derivatives which selectively inhibit microtubule affinity regulating kinase (MARK) and are therefore useful for the treatment or prevention of Alzheimer's disease. Pharmaceutical compositions and methods of use are also included.
公开/授权文献
- US20110195933A1 PYRAZOLO[1,5-A]PYRIDINES AS MARK INHIBITORS 公开/授权日:2011-08-11
信息查询