Invention Grant
- Patent Title: Cyclohexyl-azetidinyl antagonists of CCR2
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Application No.: US13161572Application Date: 2011-06-16
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Publication No.: US08518969B2Publication Date: 2013-08-27
- Inventor: James C. Lanter , Thomas P. Markotan , Nalin Subasinghe , Zhihua Sui
- Applicant: James C. Lanter , Thomas P. Markotan , Nalin Subasinghe , Zhihua Sui
- Applicant Address: BE
- Assignee: Janssen Pharmaceutica NV
- Current Assignee: Janssen Pharmaceutica NV
- Current Assignee Address: BE
- Agent Mary A. Appollina
- Main IPC: A01N43/42
- IPC: A01N43/42 ; A61K31/47

Abstract:
The present invention comprises compounds of Formula I. wherein: R1, R2, R4, J, Q, and A are as defined in the specification. The invention also comprises a method of preventing, treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is type II diabetes, obesity and asthma. The invention also comprises a method of inhibiting CCR2 activity in a mammal by administration of a therapeutically effective amount of at least one compound of Formula I.
Public/Granted literature
- US20110312936A1 CYCLOHEXYL-AZETIDINYL ANTAGONISTS OF CCR2 Public/Granted day:2011-12-22
Information query
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