Invention Grant
US08519168B2 Process and intermediates for the synthesis of 1,2-substituted 3,4-dioxo-1-cyclobutene compounds
有权
用于合成1,2-取代的3,4-二氧代-1-环丁烯化合物的方法和中间体
- Patent Title: Process and intermediates for the synthesis of 1,2-substituted 3,4-dioxo-1-cyclobutene compounds
- Patent Title (中): 用于合成1,2-取代的3,4-二氧代-1-环丁烯化合物的方法和中间体
-
Application No.: US12665913Application Date: 2008-07-01
-
Publication No.: US08519168B2Publication Date: 2013-08-27
- Inventor: Xiaoyong Fu , Frank Bruno Guenter , Agnes S. Kim-Meade , Kenneth Stanley Matthews , Mathew Thomas Maust , Timothy L. McAllister , Gerald Werne , Jason L. Winters , Jianguo Yin , Shuyi Zhang
- Applicant: Xiaoyong Fu , Frank Bruno Guenter , Agnes S. Kim-Meade , Kenneth Stanley Matthews , Mathew Thomas Maust , Gerald Werne , Jason L. Winters , Jianguo Yin , Shuyi Zhang , David J. Moloznik
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Eric A. Meade; Valerie J. Camara
- International Application: PCT/US2008/008187 WO 20080701
- International Announcement: WO2009/005801 WO 20090108
- Main IPC: C07D307/40
- IPC: C07D307/40
Abstract:
This application discloses a novel process for the preparation of 1,2-substituted 3,4-dioxo-1-cyclobutene compounds, which have utility, for example, in the treatment of CXC chemokine-mediated diseases, and intermediates useful in the synthesis thereof.
Public/Granted literature
- US20110160469A1 PROCESS AND INTERMEDIATES FOR THE SYNTHESIS OF 1,2-SUBSTITUTED 3,4-DIOXO-1-CYCLOBUTENE COMPOUNDS Public/Granted day:2011-06-30
Information query
