The present disclosure provides a transmission power control method for a physical uplink shared channel, including: when there is only uplink control information but no uplink shared channel data sent over the physical uplink shared channel, the transmission power of the physical uplink shared channel is set according to the total number of bits contained in a channel quality indication signaling and its corresponding cyclic redundancy check as well as an amplitude offset. The present disclosure also provides a transmission power control system for a physical uplink shared channel. The method and system described in the present disclosure can ensure the overall performance of a system.