The invention provides a multi-piece solid golf ball having a core, an envelope layer enclosing the core, an intermediate layer enclosing the envelope layer, and a cover which encloses the intermediate layer and has formed on a surface thereof a plurality of dimples. The core is formed primarily of a rubber material and has a diameter of at least 31 mm, the envelope layer and the intermediate layer are each formed primarily of the same or different resin materials, and the cover is formed primarily of polyurethane. The envelope layer, intermediate layer and cover have thicknesses which satisfy the relationship cover thickness cover surface hardness. The golf ball has an excellent flight performance and controllability that are acceptable to professionals and other skilled golfers, while also having an excellent durability to cracking on repeated impact and an excellent scuff resistance.