发明授权
US08524695B2 Modified release formulations of (6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine and methods of using the same
有权
(6R)-4,5,6,7-四氢-N6-丙基-2,6-苯并噻唑二胺的改性释放制剂及其使用方法
- 专利标题: Modified release formulations of (6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine and methods of using the same
- 专利标题(中): (6R)-4,5,6,7-四氢-N6-丙基-2,6-苯并噻唑二胺的改性释放制剂及其使用方法
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申请号: US12048890申请日: 2008-03-14
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公开(公告)号: US08524695B2公开(公告)日: 2013-09-03
- 发明人: Michael E. Bozik , Thomas Petzinger, Jr. , Valentin Gribkoff
- 申请人: Michael E. Bozik , Thomas Petzinger, Jr. , Valentin Gribkoff
- 申请人地址: US PA Pittsburgh
- 专利权人: Knopp Neurosciences, Inc.
- 当前专利权人: Knopp Neurosciences, Inc.
- 当前专利权人地址: US PA Pittsburgh
- 代理机构: Pepper Hamilton LLP
- 主分类号: A01N43/00
- IPC分类号: A01N43/00 ; A01N43/78 ; A61K31/33 ; A61K31/425
摘要:
Modified release pharmaceutical compositions (controlled release, sustained release, and/or extended release) of the R-(+) enantiomer of pramipexole (RPPX) and methods of using such compositions for the treatment of neurodegenerative diseases, or those related to mitochondrial dysfunction or increased oxidative stress are disclosed.
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