发明授权
US08524705B2 2-oxo-2-(2-phenyl-5,6,7,8-tetrahydro-indolizin-3-yl)-acetamide derivatives and related compounds as antifungal agents
有权
2-氧代-2-(2-苯基-5,6,7,8-四氢 - 中氮茚-3-基) - 乙酰胺衍生物和相关化合物作为抗真菌剂
- 专利标题: 2-oxo-2-(2-phenyl-5,6,7,8-tetrahydro-indolizin-3-yl)-acetamide derivatives and related compounds as antifungal agents
- 专利标题(中): 2-氧代-2-(2-苯基-5,6,7,8-四氢 - 中氮茚-3-基) - 乙酰胺衍生物和相关化合物作为抗真菌剂
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申请号: US12601284申请日: 2008-05-21
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公开(公告)号: US08524705B2公开(公告)日: 2013-09-03
- 发明人: Lloyd James Payne , Robert Downham , Graham Edward Morris Sibley , Philip Edwards , Gareth Morse Davies
- 申请人: Lloyd James Payne , Robert Downham , Graham Edward Morris Sibley , Philip Edwards , Gareth Morse Davies
- 申请人地址: GB Greater Manchester
- 专利权人: F2G Limited British Body Corporate
- 当前专利权人: F2G Limited British Body Corporate
- 当前专利权人地址: GB Greater Manchester
- 代理机构: Fulbright & Jaworski L.L.P.
- 优先权: GB0710121.5 20070525
- 国际申请: PCT/GB2008/001738 WO 20080521
- 国际公布: WO2008/145963 WO 20081204
- 主分类号: A61K31/437
- IPC分类号: A61K31/437 ; A61K31/496 ; A61K31/551 ; A61K31/5377 ; A01N43/90
摘要:
The invention provides compounds of formula (I), and pharmaceutically and agriculturally acceptable salts thereof: wherein: R1, R2, R3, R4, R5, R6, R7, R8, A1, L1 and n are as defined herein. These compounds and their pharmaceutically acceptable salts are useful in the manufacture of medicaments for use in the prevention or treatment of a fungal disease. Compounds of formula (I), and agriculturally acceptable salts thereof, may also be used as agricultural fungicides.
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