发明授权
- 专利标题： Pyridyl derivatives as CFTR modulators
- 专利标题（中）： 吡啶衍生物作为CFTR调节剂
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申请号： US13533326申请日： 2012-06-26
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公开(公告)号： US08524910B2公开(公告)日： 2013-09-03
- 发明人: Sara Hadida Ruah , Mark Miller , Jinglan Zhou , Brian Bear , Peter Grootenhuis
- 申请人： Sara Hadida Ruah , Mark Miller , Jinglan Zhou , Brian Bear , Peter Grootenhuis
- 申请人地址： US MA Cambridge
- 专利权人： Vertex Pharmaceuticals Incorporated
- 当前专利权人： Vertex Pharmaceuticals Incorporated
- 当前专利权人地址： US MA Cambridge
- 代理商 Michael J. DiVerdi
- 主分类号： A61K31/44
- IPC分类号： A61K31/44 ; C07D405/00
摘要：
The present invention relates to modulators of Formula I and the accompanying definitions herein of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”), compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases such as cystic fibrosis using such modulators.
公开/授权文献
- US20120270869A1 PYRIDYL DERIVATIVES AS CFTR MODULATORS 公开/授权日：2012-10-25
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