A wheel position determination system and method to count wheel revolutions in a wheel unit of a tire monitoring system. An indication of the count is transmitted, optionally along with an indication of a left/right side position of the wheel on the vehicle, and an identification unique to the transmitting wheel unit, to a central controller of the tire monitoring system. In the central controller of the tire monitoring system, the count is compared with wheel speed information for the vehicle, such as from an ABS system, to determine if one wheel on each side of the vehicle is rotating at a different speed. Based at least in part upon a determination that each wheel speed is unique, a determination of wheel location may be made.