Invention Grant
- Patent Title: AAV vectors for in vivo gene therapy of rheumatoid arthritis
- Patent Title (中): 用于体内基因治疗类风湿关节炎的AAV载体
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Application No.: US10569851Application Date: 2004-09-01
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Publication No.: US08529885B2Publication Date: 2013-09-10
- Inventor: Paul Peter Tak , Christian Jorgensen
- Applicant: Paul Peter Tak , Christian Jorgensen
- Applicant Address: NL Amsterdam FR Paris
- Assignee: Academisch Medisch Centrum,Institut National de la Sante et de la Recherche Medicale
- Current Assignee: Academisch Medisch Centrum,Institut National de la Sante et de la Recherche Medicale
- Current Assignee Address: NL Amsterdam FR Paris
- Agency: McDonnell Boehnen Hulbert & Berghoff LLP
- Priority: NLNL03/611 20030901
- International Application: PCT/NL2004/000607 WO 20040901
- International Announcement: WO2005/021768 WO 20050310
- Main IPC: A61K48/00
- IPC: A61K48/00 ; A61K31/70 ; C12N15/63 ; A01K67/00
Abstract:
The present invention relates to the field of adeno-associated virus (AAV) based gene therapy, in particular in vivo gene therapy, of rheumatoid arthritis (RA). The invention provides recombinant AAV virions being highly efficient in delivering genes encoding therapeutic proteins to the arthritic joints, and method for using such virions in in vivo gene therapy.
Public/Granted literature
- US20070104687A1 AAV vectors for in vivo gene therapy of rheumatoid arthritis Public/Granted day:2007-05-10
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