Invention Grant
- Patent Title: Method for polymerizing a small oligonucleotide, and use of a high-molecular oligonucleotide prepared by the polymerization method
- Patent Title (中): 聚合小寡核苷酸的方法，以及使用通过聚合法制备的高分子寡核苷酸
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Application No.: US13142876Application Date: 2010-03-02
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Publication No.: US08530047B2Publication Date: 2013-09-10
- Inventor: KwangMeyung Kim , Ick Chan Kwon , Kui Won Choi , Seung Young Lee , In Chan Youn , Myung Sook Huh , So Jin Lee
- Applicant: KwangMeyung Kim , Ick Chan Kwon , Kui Won Choi , Seung Young Lee , In Chan Youn , Myung Sook Huh , So Jin Lee
- Applicant Address: KR Seoul
- Assignee: Korea Institute of Science and Technology
- Current Assignee: Korea Institute of Science and Technology
- Current Assignee Address: KR Seoul
- Agency: Staas & Halsey LLP
- Priority: KR10-2009-0042273 20090514
- International Application: PCT/KR2010/001296 WO 20100302
- International Announcement: WO2010/131835 WO 20101118
- Main IPC: B32B5/16
- IPC: B32B5/16
Abstract:
The oligonucleotide polymerization method of the present invention is advantageous in that an oligonucleotide with a small molecular weight can be easily polymerized into high-molecular weight oligonucleotides. Further, the high-molecular oligonucleotide prepared by the method of the present invention can bind to hydrophilic high-molecular materials or inorganic materials, and then can be stably delivered to a living body. Therefore, the high-molecular oligonucleotide prepared by the method of the present invention can be widely used for treating various diseases.
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