Invention Grant
- Patent Title: Defective Sindbis viral vector comprising an anti-tumor gene
- Patent Title (中): 含有抗肿瘤基因的辛德毕斯病毒载体不良
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Application No.: US11877018Application Date: 2007-10-23
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Publication No.: US08530232B2Publication Date: 2013-09-10
- Inventor: Alicia Hurtado , Daniel Meruelo
- Applicant: Alicia Hurtado , Daniel Meruelo
- Applicant Address: US NY New York
- Assignee: New York University
- Current Assignee: New York University
- Current Assignee Address: US NY New York
- Agency: Fish & Richardson P.C.
- Main IPC: C12N15/00
- IPC: C12N15/00
Abstract:
Disclosed herein are new defective Sindbis viral vectors made from wild type Ar-339 Sindbis virus, with differences in replicase and envelope proteins between JT vectors and consensus Sindbis virus sequences, and also between JT and Ar-339 vectors. Also disclosed are plasmids used for the production of the vectors, methods for producing the vectors, methods for treating mammals suffering from tumors and pharmaceutical formulations for use in the treatment methods.
Public/Granted literature
- US20080096837A1 DEFECTIVE SINDBIS VIRAL VECTORS Public/Granted day:2008-04-24
Information query
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