发明授权
- 专利标题: Pharmaceutical composition of nanoparticles
- 专利标题(中): 纳米粒子的药物组成
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申请号: US13776111申请日: 2013-02-25
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公开(公告)号: US08535640B1公开(公告)日: 2013-09-17
- 发明人: Hsing-Wen Sung , Ha Giang Thi Nguyen , Fang Yi Su , Li-Wen Hsu , Er-Yuan Chung , Hosheng Tu
- 申请人: Hsing-Wen Sung , Ha Giang Thi Nguyen , Fang Yi Su , Li-Wen Hsu , Er-Yuan Chung , Hosheng Tu
- 申请人地址: US CA Newport Beach TW Hsinchu
- 专利权人: GP Medical, Inc.,National Tsing Hua University
- 当前专利权人: GP Medical, Inc.,National Tsing Hua University
- 当前专利权人地址: US CA Newport Beach TW Hsinchu
- 主分类号: A61K51/00
- IPC分类号: A61K51/00
摘要:
The invention discloses a composition of nanoparticles composed of positively charged chitosan, one negatively charged substrate, and optionally a zero-charge compound or at least one tumor necrosis factor inhibitor for oral delivery. The chitosan-based nanoparticles are characterized with a positive surface charge and enhanced permeability for oral drug delivery.
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