Invention Grant
US08536332B2 Modulating signal transduction pathways with substituted pyridol [2,3-b] pyrazines
失效
用取代的吡啶并[2,3-b]吡嗪调节信号转导通路
![Modulating signal transduction pathways with substituted pyridol [2,3-b] pyrazines](/docs/US/2013-09-17/US08536332B2/abs.jpg.600x600.jpg)
- Patent Title: Modulating signal transduction pathways with substituted pyridol [2,3-b] pyrazines
- Patent Title (中): 用取代的吡啶并[2,3-b]吡嗪调节信号转导通路
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Application No.: US13455187Application Date: 2012-04-25
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Publication No.: US08536332B2Publication Date: 2013-09-17
- Inventor: Matthias Gerlach , Irene Seipelt , Eckhard Guenther , Emmanuel Polymeropoulos , Tilmann Schuster , Eckhard Claus
- Applicant: Matthias Gerlach , Irene Seipelt , Eckhard Guenther , Emmanuel Polymeropoulos , Tilmann Schuster , Eckhard Claus
- Applicant Address: DE Frankfurt am Main
- Assignee: Aeterna Zentaris GmbH
- Current Assignee: Aeterna Zentaris GmbH
- Current Assignee Address: DE Frankfurt am Main
- Agency: Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
- Priority: EP07107976 20070510
- Main IPC: C07D471/00
- IPC: C07D471/00
![Modulating signal transduction pathways with substituted pyridol [2,3-b] pyrazines](/abs-image/US/2013/09/17/US08536332B2/abs.jpg.150x150.jpg)
Abstract:
Method of modulating ras-Raf-Mek-Erk signal transduction pathway, PI3K-Akt signal transduction pathway and/or SAPK signal transduction pathway with a pyrido[2,3-b]pyrazine of formula (Ia).
Public/Granted literature
- US20120209050A1 NOVEL PYRIDOPYRAZINE DERIVATIVES, PROCESS OF MANUFACTURING AND USES THEREOF Public/Granted day:2012-08-16
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