Methods and related systems are described for the detection of nuclear radiation. The system can include a tool body adapted to be deployed in a wellbore and a scintillator material that intrinsically generates radiation. The scintillator material is mounted within the tool body. A photodetection system is coupled to the scintillator material, and mounted within the tool body. Features in a spectrum associated with a scintillation material's intrinsic radioactive decay are used for the determination of one or more parameter's of the response function of the radiation detector system.