Multiple-Input Multiple-Output (MIMO) systems and methods are provided for enabling network MIMO among base stations (BSs) and a mobile station (MS). A BS configure a network MIMO zone based on an indication of at least one other BS eligible for network MIMO. The network MIMO zone is defined by resources having at least time and frequency dimensions allocated for master transmission under control of the BS, or slave transmission under control of the other BS eligible for network MIMO. The BS can transmit data on the network MIMO zone to the MS. Where there is no data to transmit to the MS, the BS may transmit data on the network MIMO zone to another MS. To configure the network MIMO zone, the BS may look up in a table combinations of the eligible BSs associated with the indication.