发明授权
- 专利标题: Complement receptor 1 and 2 fusion proteins
- 专利标题(中): 补体受体1和2融合蛋白
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申请号: US13162434申请日: 2011-06-16
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公开(公告)号: US08540997B2公开(公告)日: 2013-09-24
- 发明人: Stephen Tomlinson , V. Michael Holers
- 申请人: Stephen Tomlinson , V. Michael Holers
- 申请人地址: US SC Charleston US CO Denver
- 专利权人: MUSC Foundation for Research Development,The Regents of the University of Colorado, a body corporate
- 当前专利权人: MUSC Foundation for Research Development,The Regents of the University of Colorado, a body corporate
- 当前专利权人地址: US SC Charleston US CO Denver
- 代理机构: Clark & Elbing LLP
- 代理商 Kristina Bieker-Brady
- 主分类号: A61K39/00
- IPC分类号: A61K39/00
摘要:
Modulation of the complement system represents a therapeutic modality for numerous pathologic conditions associated with complement activation. In a strategy to prepare complement inhibitors that are targeted to sites of complement activation and disease, compositions comprising a complement inhibitor linked to complement receptor (CR) 2 are disclosed. The disclosed are compositions can be used in methods of treating pathogenic diseases and inflammatory conditions by modulating the complement system.
公开/授权文献
- US20120015872A1 COMPLEMENT RECEPTOR 2 TARGETED COMPLEMENT MODULATORS 公开/授权日:2012-01-19
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