Invention Grant
US08541457B2 Aminothiazole derivatives as human stearoyl-CoA desaturase inhibitors
失效
氨基噻唑衍生物作为人类硬脂酰CoA去饱和酶抑制剂
- Patent Title: Aminothiazole derivatives as human stearoyl-CoA desaturase inhibitors
- Patent Title (中): 氨基噻唑衍生物作为人类硬脂酰CoA去饱和酶抑制剂
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Application No.: US11916243Application Date: 2006-06-05
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Publication No.: US08541457B2Publication Date: 2013-09-24
- Inventor: Jianmin Fu , Duanjie Hou , Rajender Kamboj , Vishnumurthy Kodumuru , Natalia Pokrovskaia , Vandna Raina , Shaoyi Sun , Serguei Sviridov , Zaihui Zhang
- Applicant: Jianmin Fu , Duanjie Hou , Rajender Kamboj , Vishnumurthy Kodumuru , Natalia Pokrovskaia , Vandna Raina , Shaoyi Sun , Serguei Sviridov , Zaihui Zhang
- Applicant Address: CA Burnaby, B.C.
- Assignee: Xenon Pharmaceuticals Inc.
- Current Assignee: Xenon Pharmaceuticals Inc.
- Current Assignee Address: CA Burnaby, B.C.
- Agency: Seed IP Law Group PLLC
- International Application: PCT/US2006/021660 WO 20060605
- International Announcement: WO2007/130075 WO 20071115
- Main IPC: A01N43/78
- IPC: A01N43/78 ; A61K31/425
Abstract:
Methods of treating an SCD-mediated disease or condition in a mammal, preferably a human, are disclosed, wherein the methods comprise administering to a mammal in need thereof a compound of formula (I), where V, W, R1, R2, R3 and R4 are defined herein. Pharmaceutical compositions comprising the compounds of formula (I) are also disclosed.
Public/Granted literature
- US20100152187A1 AMINOTHIAZOLE DERIVATIVES AS HUMAN STEAROYL-COA DESATURASE INHIBITORS Public/Granted day:2010-06-17
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