发明授权
US08541457B2 Aminothiazole derivatives as human stearoyl-CoA desaturase inhibitors
失效
氨基噻唑衍生物作为人类硬脂酰CoA去饱和酶抑制剂
- 专利标题： Aminothiazole derivatives as human stearoyl-CoA desaturase inhibitors
- 专利标题（中）： 氨基噻唑衍生物作为人类硬脂酰CoA去饱和酶抑制剂
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申请号： US11916243申请日： 2006-06-05
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公开(公告)号： US08541457B2公开(公告)日： 2013-09-24
- 发明人: Jianmin Fu , Duanjie Hou , Rajender Kamboj , Vishnumurthy Kodumuru , Natalia Pokrovskaia , Vandna Raina , Shaoyi Sun , Serguei Sviridov , Zaihui Zhang
- 申请人： Jianmin Fu , Duanjie Hou , Rajender Kamboj , Vishnumurthy Kodumuru , Natalia Pokrovskaia , Vandna Raina , Shaoyi Sun , Serguei Sviridov , Zaihui Zhang
- 申请人地址： CA Burnaby, B.C.
- 专利权人： Xenon Pharmaceuticals Inc.
- 当前专利权人： Xenon Pharmaceuticals Inc.
- 当前专利权人地址： CA Burnaby, B.C.
- 代理机构： Seed IP Law Group PLLC
- 国际申请： PCT/US2006/021660 WO 20060605
- 国际公布： WO2007/130075 WO 20071115
- 主分类号： A01N43/78
- IPC分类号： A01N43/78 ; A61K31/425
摘要：
Methods of treating an SCD-mediated disease or condition in a mammal, preferably a human, are disclosed, wherein the methods comprise administering to a mammal in need thereof a compound of formula (I), where V, W, R1, R2, R3 and R4 are defined herein. Pharmaceutical compositions comprising the compounds of formula (I) are also disclosed.
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