The medical safety box is a system using RFID (Radio Frequency Identification) technology to ensure that correct delivery of the correct treatment in the form of medication or injection to in-hospital patients is consistently carried out. The system includes a medical box containing whatever medication or injection that needs to be administered to a specific patient. The box has a locking mechanism that can only be opened by an RFID wristband, which is worn by that same specific patient, thus assuring that the medicine in the box is administered to the correct patient.