发明授权
- 专利标题: Antibodies against domains of laminin-332
- 专利标题(中): 针对层粘连蛋白332结构域的抗体
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申请号: US13060358申请日: 2009-06-18
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公开(公告)号: US08545845B2公开(公告)日: 2013-10-01
- 发明人: Karl Tryggvason , Sirpa Anne Kristiina Salo
- 申请人: Karl Tryggvason , Sirpa Anne Kristiina Salo
- 代理机构: Fay Sharpe LLP
- 国际申请: PCT/IB2009/006404 WO 20090618
- 国际公布: WO2009/153670 WO 20091223
- 主分类号: A61K39/395
- IPC分类号: A61K39/395
摘要:
Antibodies against various domains of laminin-332 are discussed herein. The antibodies reduce the adhesion and matrix binding properties of laminin-332, inhibiting tumor growth and metastasis in vivo. Pharmaceutical compositions and methods of using the antibodies for diagnostic, prophylactic, and/or therapeutic purposes are disclosed.
公开/授权文献
- US20110243965A1 ANTIBODIES AGAINST DOMAINS OF LAMININ-332 公开/授权日:2011-10-06
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