Invention Grant
- Patent Title: Stable laquinimod preparations
- Patent Title (中): 稳定的laquinimod制剂
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Application No.: US13471175Application Date: 2012-05-14
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Publication No.: US08545885B2Publication Date: 2013-10-01
- Inventor: Muhammad Safadi , Daniella Licht , Ioana Lovinger , Aharon M. Eyal , Tomas Fristedt , Karl Jansson
- Applicant: Muhammad Safadi , Daniella Licht , Ioana Lovinger , Aharon M. Eyal , Tomas Fristedt , Karl Jansson
- Applicant Address: IL Petach-Tikva SE Lund
- Assignee: Teva Pharmaceutical Industries, Ltd.,Active Biotech, AB
- Current Assignee: Teva Pharmaceutical Industries, Ltd.,Active Biotech, AB
- Current Assignee Address: IL Petach-Tikva SE Lund
- Agency: Cooper & Dunham LLP
- Agent John P. White; Gary J. Gershik
- Main IPC: A61K9/20
- IPC: A61K9/20
Abstract:
The subject invention provides a pharmaceutical composition comprising N-ethyl-N-phenyl-1,2,-dihydro-4-hydroxy-5-chloro-1-methyl-2-oxoquinoline-3-carboxamide or the salt thereof; a pharmaceutically acceptable carrier; and not more than 0.5% w/w relative to N-ethyl-N-phenyl-1,2,-dihydro-4-hydroxy-5-chloro-1-methyl-2-oxoquinoline-3-carboxamide of 2-Chloro-6-(1-ethyl-N-methyl-2-oxoindoline-3-carboxamido)benzoic acid, 1H,3H-spiro[5-chloro-1-methylquinoline-2,4-dione-3,3′-[1]ethylindolin-[2]-one], or 5-Chloro-N-ethyl-3-hydroxy-1-methyl-2,4-dioxo-N-phenyl-1,2,3,4-tetrahydro-quinoline-3-carboxamide.
Public/Granted literature
- US20120225124A1 STABLE LAQUINIMOD PREPARATIONS Public/Granted day:2012-09-06
Information query
