发明授权
US08545935B2 On-the-fly coating of acid-releasing degradable material onto a particulate 有权
将释放酸的可降解材料即时涂布在颗粒上

On-the-fly coating of acid-releasing degradable material onto a particulate
摘要:
Methods of creating particulates coated with acid-releasing degradable material comprising the steps of: combining an acid-releasing degradable material with a solvent or a plasticizer to create a coating solution; providing a first flowing stream comprising the coating solution; providing a second flowing stream comprising particulates; and, combining the first and second flowing streams to create a third flowing stream comprising particulates coated with the coating solution. Wherein the acid-releasing degradable material comprises at least one acid-releasing degradable material selected from the group consisting of: poly(orthoester); a lactide, a poly(lactide); a glycolide; a poly(glycolide); a poly(ε-caprolactone); a poly(hydroxybutyrate); a substantially water insoluble anhydride; a poly(anhydride); a poly(amino acid); a copolymer of two or more of the above-listed compounds; and any combination thereof.
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