- 专利标题： Factor VIII polypeptide having factor VIII:C activity
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申请号： US12388665申请日： 2009-02-19
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公开(公告)号： US08546332B2公开(公告)日： 2013-10-01
- 发明人: Petrus Johannes Lenting , Jan Aart Van Mourik , Koenraad Mertens , Hans Pannekoek , Peter Turecek , Hans-Peter Schwarz , Friedrich Scheiflinger
- 申请人： Petrus Johannes Lenting , Jan Aart Van Mourik , Koenraad Mertens , Hans Pannekoek , Peter Turecek , Hans-Peter Schwarz , Friedrich Scheiflinger
- 申请人地址： NL Amsterdan
- 专利权人： Stichting Sanquin Bloedvoorziening
- 当前专利权人： Stichting Sanquin Bloedvoorziening
- 当前专利权人地址： NL Amsterdan
- 代理机构： Perkins Coie LLP
- 优先权： AT1872/98 19981110
- 主分类号： A61K38/37
- IPC分类号： A61K38/37 ; A61K38/00
摘要：
Factor VIII polypeptides having FVIII:C activity that contain modifications in the A3 and/or C1 and/or C2 domains of the sequence of the light chain of Factor VIII, characterized by the binding affinity to low density lipoprotein receptor protein, and methods for producing the same.
公开/授权文献
- US20110118188A1 FACTOR VIII POLYPEPTIDE HAVING FACTOR VIII:C ACTIVITY 公开/授权日：2011-05-19
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