发明授权
US08546407B2 Ortho-condensed pyridine and pyrimidine derivatives (e.g., purines) as protein kinases inhibitors
有权
正构缩合的吡啶和嘧啶衍生物(如嘌呤)作为蛋白激酶抑制剂
- 专利标题: Ortho-condensed pyridine and pyrimidine derivatives (e.g., purines) as protein kinases inhibitors
- 专利标题(中): 正构缩合的吡啶和嘧啶衍生物(如嘌呤)作为蛋白激酶抑制剂
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申请号: US11577963申请日: 2005-10-25
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公开(公告)号: US08546407B2公开(公告)日: 2013-10-01
- 发明人: Valerio Berdini , Robert George Boyle , Gordon Saxty , David Winter Walker , Steven John Woodhead , Paul Graham Wyatt , Alastair Donald , John Caldwell , Ian Collins , Tatiana Faria Da Fonseca
- 申请人: Valerio Berdini , Robert George Boyle , Gordon Saxty , David Winter Walker , Steven John Woodhead , Paul Graham Wyatt , Alastair Donald , John Caldwell , Ian Collins , Tatiana Faria Da Fonseca
- 申请人地址: GB Cambrdige GB London GB London
- 专利权人: Astex Therapeutics Limited,The Institute of Cancer Research: Royal Cancer Hospital,Cancer Research Technology Limited
- 当前专利权人: Astex Therapeutics Limited,The Institute of Cancer Research: Royal Cancer Hospital,Cancer Research Technology Limited
- 当前专利权人地址: GB Cambrdige GB London GB London
- 代理机构: Heslin Rothenberg Farley & Mesiti P.C.
- 优先权: GB0423655.0 20041025
- 国际申请: PCT/GB2005/004119 WO 20051025
- 国际公布: WO2006/046024 WO 20060504
- 主分类号: C07D487/04
- IPC分类号: C07D487/04 ; A61K31/519 ; A61P35/00
摘要:
The invention provides a compound for use as a protein kinase B inhibitor, the compound being a compound of the formula (Ic) or salts, tautomers or N-oxides thereof.