发明授权
US08546429B2 1,2,3-trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto
失效
1,2,3-三取代的芳基和杂芳基衍生物作为代谢的调节剂以及与之相关的疾病的预防和治疗
- 专利标题： 1,2,3-trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto
- 专利标题（中）： 1,2,3-三取代的芳基和杂芳基衍生物作为代谢的调节剂以及与之相关的疾病的预防和治疗
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申请号： US12903976申请日： 2010-10-13
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公开(公告)号： US08546429B2公开(公告)日： 2013-10-01
- 发明人: Robert M. Jones , Graeme Semple , Yifeng Xiong , Young-Jun Shin , Albert S. Ren , Imelda Calderon , Beatriz Fioravanti , Jin Sun Karoline Choi , Juerg Lehmann , Marc Bruce
- 申请人： Robert M. Jones , Graeme Semple , Yifeng Xiong , Young-Jun Shin , Albert S. Ren , Imelda Calderon , Beatriz Fioravanti , Jin Sun Karoline Choi , Juerg Lehmann , Marc Bruce
- 申请人地址： US CA San Diego
- 专利权人： Arena Pharmaceuticals, Inc.
- 当前专利权人： Arena Pharmaceuticals, Inc.
- 当前专利权人地址： US CA San Diego
- 代理机构： Fish & Richardson P.C.
- 代理商 Lyle W. Spruce
- 主分类号： C07D211/46
- IPC分类号： C07D211/46 ; C07D401/14 ; A61K31/4545
摘要：
The present invention relates to certain trisubstituted aryl and heteroaryl derivatives of Formula (I) that are modulators of metabolism. Accordingly, compounds of the present invention are useful in the prophylaxis or treatment of metabolic disorders and complications thereof, such as, diabetes and obesity.