- 专利标题： Proteasome inhibitors and methods of using the same
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申请号： US13249738申请日： 2011-09-30
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公开(公告)号： US08546608B2公开(公告)日： 2013-10-01
- 发明人: Raffaella Bernardini , Alberto Bernareggi , Paolo G. Cassara , Sankar Chatterjee , Germano D'Arasmo , Sergio De Munari , Edmondo Ferretti , Mohamed Iqbal , Ernesto Menta , Patricia A. Messina McLaughlin , Ambrogio Oliva
- 申请人： Raffaella Bernardini , Alberto Bernareggi , Paolo G. Cassara , Sankar Chatterjee , Germano D'Arasmo , Sergio De Munari , Edmondo Ferretti , Mohamed Iqbal , Ernesto Menta , Patricia A. Messina McLaughlin , Ambrogio Oliva
- 申请人地址： US PA Frazer
- 专利权人： Cephalon, Inc.
- 当前专利权人： Cephalon, Inc.
- 当前专利权人地址： US PA Frazer
- 代理机构： Woodcock Washburn LLP
- 主分类号： C07F5/02
- IPC分类号： C07F5/02
摘要：
The present invention provides boronic acid compounds, boronic esters, and compositions thereof that can modulate apoptosis such as by inhibition of proteasome activity. The compounds and compositions can be used in methods of inducing apoptosis and treating diseases such as cancer and other disorders associated directly of indirectly with proteasome activity.
公开/授权文献
- US20120041196A1 Proteasome Inhibitors and Methods of Using the Same 公开/授权日：2012-02-16