发明授权
- 专利标题： Systems and methods for rapid identification of nucleic acid variants
- 专利标题（中）： 用于快速鉴定核酸变体的系统和方法
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申请号： US12616422申请日： 2009-11-11
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公开(公告)号： US08551738B2公开(公告)日： 2013-10-08
- 发明人: David J. Ecker , Steven A. Hofstadler , Thomas A. Hall , Kristin Sannes-Lowery
- 申请人： David J. Ecker , Steven A. Hofstadler , Thomas A. Hall , Kristin Sannes-Lowery
- 申请人地址： US CA Carlsbad
- 专利权人： Ibis Biosciences, Inc.
- 当前专利权人： Ibis Biosciences, Inc.
- 当前专利权人地址： US CA Carlsbad
- 代理机构： Casimir Jones S.C.
- 代理商 Christopher C. Sappenfield
- 主分类号： C12P19/34
- IPC分类号： C12P19/34 ; C12Q1/68 ; C12M1/00
摘要：
There is a need for nucleic acid analysis which is both specific and rapid, and in which no nucleic acid sequencing is required. The present invention addresses this need, among others by providing a method of nucleic acid amplification of overlapping sub-segments of a nucleic acid followed by molecular mass measurement of resulting amplification products by mass spectrometry, and determination of the base compositions of the amplification products.
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