- 专利标题： Peptide vaccines for cancers expressing MPHOSPH1 or DEPDC1 polypeptides
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申请号： US13562250申请日： 2012-07-30
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公开(公告)号： US08552146B2公开(公告)日： 2013-10-08
- 发明人: Tomoaki Fujioka , Yusuke Nakamura , Takuya Tsunoda , Ryuji Osawa , Midori Shida
- 申请人： Tomoaki Fujioka , Yusuke Nakamura , Takuya Tsunoda , Ryuji Osawa , Midori Shida
- 申请人地址： JP Kanagawa
- 专利权人： OncoTherapy Science, Inc.
- 当前专利权人： OncoTherapy Science, Inc.
- 当前专利权人地址： JP Kanagawa
- 代理机构： Kilpatrick Townsend & Stockton LLP
- 主分类号： C07K5/00
- IPC分类号： C07K5/00 ; C12P21/00
摘要：
The present invention provides peptides having an amino acid sequence as set forth in SEQ ID NO: 7, 8, 9, 10, 11, 12, 192, 195, 197, 209, 225, 226, 228, 230, 240, 241, 243, 244, 249, 253, 254 or 255, as well as peptides having the above-mentioned amino acid sequences in which 1, 2, or several amino acids are substituted, deleted, or added, wherein the peptides possess cytotoxic T cell inducibility. The present invention also provides drugs for treating or preventing a disease associated with the over-expression of MPHOSPH1 and/or DEPDC1, e.g. cancers, containing these peptides as an active ingredient. The peptides of the present invention can also be used as vaccines.
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